Comment on "Local impermeant anions establish the neuronal chloride concentration".

نویسندگان

  • Juha Voipio
  • Walter F Boron
  • Stephen W Jones
  • Ulrich Hopfer
  • John A Payne
  • Kai Kaila
چکیده

Glykys et al. (Reports, 7 February 2014, p. 670) conclude that, rather than ion transporters, "local impermeant anions establish the neuronal chloride concentration" and thereby determine "the magnitude and direction of GABAAR currents at individual synapses." If this were possible, perpetual ion-motion machines could be constructed. The authors' conclusions conflict with basic thermodynamic principles.

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عنوان ژورنال:
  • Science

دوره 345 6201  شماره 

صفحات  -

تاریخ انتشار 2014